PRESENT LAB MEMBERS
Gio was born in the tiny fishing town of Castellammare del Golfo, Sicily, Italy. Gio and his family immigrated to the US when he was 4-years old and he grew up in New York. Gio received his BA in Biology from Boston University. While at BU Gio was greatly inspired by the late evolutionary biologist, Lynn Margulis, where he worked in Lynn's lab for about three years. Gio also studied history and theology at the Università Pontificia Gregoriana, Rome, Italy. After Boston, Rome and three years of working as a tech he joined the biology graduate program at Brandeis University. As a grad student Gio trained with James E. Haber at Brandeis, and then he went on to be a Damon Runyon Cancer Foundation post-doctoral fellow at MIT with Terry L. Orr-Weaver. Gio was appointed to his first faculty position at the University of Arizona, Tucson, in 2002, and promoted to associate professor with tenure in 2008. He moved his lab to the Geisel School of Medicine at Dartmouth in 2012. Gio was promoted to full professor with tenure in 2016, where he is currently the Oscar M. Cohn Professor in the Department of Molecular and Systems Biology. In 2015 Gio received a 5-year NIH Director's Pioneer Award for high-risk, high-reward research in "Trans-generational inheritance of social behavior." Work in the lab has also been or is currently funded by the American Federation of Aging Research, National Science Foundation and the Defense Advanced Research Projects Agency (DARPA) at the US Department of Defense.
Gio's other passion is homesteading. Check back soon for a link to the Bosco family Orchard at Blackberry Hill in Thetford, Vermont.
MD/PhD Student in the Quantitative Biomedical Sciences (QBS) program.
Marek started the MD-PhD program at Dartmouth in 2015 and joined Bosco lab in the spring of 2018 as a student in the Quantitative Biomedical Sciences program. After growing up in Czechia, he received his BA in Neuroscience and Behavior from Columbia University. He is interested in interdisciplinary approaches that combine molecular biology and computational analysis. In his current project in collaboration with Dr. Bryan Luikart, he studies gene interactions in a mouse model of autism in order to identify novel therapeutic targets.
In his spare time, Marek enjoys playing tennis, is a fierce competitor in backyard badminton, and also enjoys escape the room games, eating popcorn, and sharing music with his friends while carpooling.
Emily is a post-doctoral researcher. Emily joined the Bosco lab in 2016. She received her BA in Biochemistry from Colgate University, and her PhD in Molecular Cancer Biology from Dartmouth College. Her current projects focus on the impact of misregulated condensin II on cell differentiation and cancer development.
Emily’s other passions are rock climbing, yoga, and baked goods.
Vibhuti joined the Dartmouth MCB grad program in 2014 and joined the lab in the spring of 2015. Vibhuti received her B.S. in Cell and Molecular Biology from the University of Texas at Austin. Her current project is focused on condensin II activities and their ability to reshape interphase chromatin structure and nuclear architecture in human cells.
Vibhuti's other passion in life is art, watching cute animal videos and sleeping.
Vicki joined the lab in 2012. Vicki is our lab tech, manages the lab, and takes very good care of all our precious fly stocks. Vicki was born and raised in New Hampshire; aside from running away from the cold Northeast and living in Puerto Rico in years past, she now lives in NH and is a true New Englander.
Vicki loves to cook and listen to music.
Katie joined the Dartmouth MCB grad program in 2015 and joined the lab in the summer of 2016. Katie received her B.S. in Chemistry and Medical Biology from the University of New England in Biddeford, Maine. Her current project is focused on identifying neural circuits of the Drosophila brain that control predator perception and predator-induced behaviors. Katie is also interested in social learning and is developing a Cornelia de Lange Syndrome Drosophila model that will focus on aspects of social learning and behavior.
Katie's other passion in life is running, hiking and playing video games.
Madhu joined the lab in 2017 as post-doctoral research fellow. After completing her PhD and NCBS in Bangalore, India, she received a prestigious 3-year research fellowship from the Human Frontiers Research Foundation. Madhu is elucidating neuronal circuitry of the Drosophila brain that controls egglaying and reproductive behavior. Madhu is from Kereyagalahalli (it’s a small village in the district of Chitradurga, Karnataka), and did her Bacholers and Masters studies (in Genetics) at the University of Mysore, Karnataka.
When not in the lab, Madhu likes cooking, gardening, DIY, hiking and love reading KANNADA books.
Shiva is a post-doctoral research fellow. He joined the lab in 2017 and is working on mouse models of autism and age dependent decline of memory in collaboration with Dr. Bryan Luikart. Shiva seeks to understand how different genetic factors interact to accelerate or mitigate the effects of aging on learning, memory and social behavior.
Shiva received his Bachelors in Biotechnology, Master's and PhD in Genetics from University of Mysore, Karnataka, India.
When not in the lab Shiva likes to play with his daughter, cooking, listening to TED talks/music and working out at the gym.
Kamran started in MCB graduate program at Dartmouth in 2017 and joined Bosco Lab in the Fall of 2019. Born and raised in Pakistan, Kamran received his BS in Biotechnology from FC College and MS in Biology from LUMS in Lahore, Pakistan. His current project involves identifying proteins that may rescue Pten-mediated changes in neurons of a mouse model of Autism, and thus serve as new targets for therapy.
In his spare time, Kamran loves to cook desi food whilst listening to Coke Studio Pakistan.
Jasmine is a Dartmouth junior, and she has been working in the lab for over a year now. Jasmine’s collaborative work with Shiva, a post-doc in the lab, seeks to understand how mutations in the mouse PTEN and Fragile-X genes interact to give abnormal neuronal growth. Jasmine’s project will help us better understand how different genetic factors contribute to human conditions like autism spectrum disorders.
Cali is currently a senior at UCLA majoring in neuroscience. Cali spent the summer of 2019 with us and was mentored by Madhu. Cali used fruit fly genetics to map the expression pattern of nearly all the known neuropeptides. “Nearly all” is actually a lot of genes, a lot of crosses, and lots of microscope time. We really hope Cali decides to apply to Dartmouth when it comes to grad programs. She’s great!
Jacob is a recent high school graduate of Thetford Academy in Vermont. He is currently taking a gap year before he starts his college studies at Yale in the Fall of 2020. Jacob is an image analysis machine, and together with Shiva and Jasmine, is producing very impressive analysis of mutant and wild-type mouse hippocampus cells. Jacob is helping us understand whether addition of Fragile-X mutations in cells that are already missing PTEN function do better or worse over time. Mutations in each of these genes are known to cause autism in humans, but no one knows how having both mutations might affect behavior and cognition.
PAST MEMBERS OF THE BOSCO LAB
Elle Nutter, Former QBS Student. Currently post-doc at Case Western Reserve University with William Bush.
Julianna Lita Bozler, Former MCB Student. Currently Jane Coffin Childs post-doc at UPENN Medical School with Roberto Bonasio.
Balint Kacsoh, Former MCB Student. Currently post-doc at UPENN Medical School with Shelley Berger.
Sassan Hodge, Former Research Assistant. Currently working at Dartmouth-Hitchcock Hospital Diagnostic Labs.
Stephen Barton, Former Research Tech. Currently science research in Maine.
Huy Nguyen, Former Grad Student. Currently post-doctoral fellow with Ting Wu at Harvard Medical School, Boston, MA.
Heather Wallace, Former Post-Doc. Currently senior science writer and communications specialist at Harvard/MIT Broad Institute.
Tom A. Hartl, Former Grad Student. Damon Runyon Fellow, Post-Doctoral Associate, Stanford University with Matthew P. Scott. Currently: Senior Scientist II, BioMarin pharmaceutical, California.
Helen F. Smith, Former Grad Student. Currently: Lecturer-AT, Gonzaga University, Spokane Washington.
Christopher R. Bauer, Former Grad Student. Currently: Senior Scientist I, BioMarin pharmaceutical, California.
Joseph Ahlander, Former Grad Student. Currently: Associate Professor (with tenure), Northeastern Sate University, OK.
Maureen Peterson, Former Grad Student. Currently: Working SF Bay Area Biotech Start-Up.
Celine Hayden, Former Post-Doc. Currently: Research and Development Manager at bioLytical Laboratories, BC, Canada. Previously Director of Vaccine R&D, Applied Biotechnology Institute, San Luis Obispo, CA.
Xiao-Jun Wang, Former Post-Doc. Currently: Senior Scientist, Exemplar Genetics, Coralville, Iowa
Sarah Sweeney, Former Undergraduate Student. Currently: UCLA Medical School
Vivian Lien, Former Undergraduate Student. Currently: MD from U of Arizona Medical School. Specialist in Cornea, Refractive, and Anterior Segment Fellow at Baylor College of Medicine.
Joy Meserve, Former Undergraduate Student. Currently: Post-doc at UPENN Medical School after graduating with a PhD in Molecular and Cellular Biology at UNC Chapel Hill.
Livia Zarnescu, Former Undergraduate Student. Currently: Making big bucks somewhere in Silicon Valley after getting her PhD in Bioengineering from Stanford University.
Meredith Roberts, Former Undergraduate Student. Currently: Engineering somewhere after graduating in Bioengineering PhD, University of Washington, Seattle, Washington.
Nathan May, Former Undergraduate Student. Currently: Attorney somewhere in the US Southwest. Graduate Student in Bioethics, Wake Forest University
Carolyn George, Former Post-Doc. Currently: Instructor at Messiah College, Grantham, PA.
Rhiannon Greywolf, Former high-school student and lab tech in the Bosco lab, Rhiannon is a recent graduate of Landmark College and artist/designer at large.